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VITAMINS

Citicoline (sodium, CDP-choline)

Citicoline (CDP-choline) supports attention and memory, and is a source of choline for the brain.

Also known as: CDP-choline, cytidine diphosphate-choline, citicoline sodium

At a glance

Form
Citicoline sodium · CDP-choline
Category
Vitamins
In an apiece formula
250 mg a day (you can change it)
Recommended intake
No recommended intake (not an essential nutrient)
Upper limit
No established UL
Studied for
Focus & memory*
Reference
NIH ODS: Choline fact sheet

What the research says

In healthy older adults with everyday memory complaints, 500 mg of citicoline a day improved memory.*

RCT, double-blind · 100 · Nakazaki, J Nutr 2021. Read the study on PubMed

Who should be careful

Our safety rules leave citicoline out of a formula, or keep the amount lower, with:

Medicines and supplements

Life stage

Always check with your doctor or pharmacist before adding a supplement if you take medication, are pregnant or nursing, or have a health condition. Stay under the upper limit from all sources combined, including multivitamins.

Questions

How much citicoline a day?

apiece formulas usually include 250 mg a day. The recommended intake for adults is No recommended intake (not an essential nutrient). Upper limit: No established UL.

What is citicoline used for?

Citicoline (CDP-choline) supports attention and memory, and is a source of choline for the brain. In apiece it is part of formulas for Focus & memory.*

Who should be careful with citicoline?

apiece’s safety rules leave it out or limit it with: Carbidopa-levodopa; Pregnancy; Breastfeeding; Trying to conceive. Check with your doctor or pharmacist if any apply to you.

Can I get citicoline in a personalized supplement?

Yes. apiece builds one daily blend around your goals and, if you have them, your lab results. Citicoline can be part of it at the amount listed, with every ingredient shown and never more than 10 capsules a day.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This page is general information, not medical advice. Check with your doctor or pharmacist before starting a supplement, especially if you take medication, are pregnant or nursing, or have a health condition. Updated 2026-10-21.