INGREDIENTS
Methylfolate: every form, compared
How the forms of methylfolate differ, and how much to take.
apiece offers 2 forms of methylfolate. Each is listed with the amount a formula usually includes.
- Methylfolate, calcium salt
L-methylfolate is the active form of folate the body uses directly to support methylation and cell health. Usual amount: 800 mcg.
- Methylfolate, glucosamine salt
This active form of folate supports healthy cell division and methylation. Usual amount: 800 mcg.
- Recommended intake
- 400 mcg DFE
- Upper limit
- 1,000 mcg a day of folic acid from supplements and fortified foods
- Reference
- NIH ODS: Folate fact sheet
Questions
Which form of methylfolate is best?
It depends on what you want it for and how your body handles it. The forms differ in how much methylfolate they carry, how they feel on the stomach and how much capsule space they take. apiece uses methylfolate, calcium salt by default and lets you choose another form.
How much methylfolate is too much?
The adult upper limit is 1,000 mcg a day of folic acid from supplements and fortified foods. Count every source, including multivitamins.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This page is general information, not medical advice. Check with your doctor or pharmacist before starting a supplement, especially if you take medication, are pregnant or nursing, or have a health condition. Updated 2026-10-21.