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BOTANICALS

Black pepper (extract, 95% piperine)

Black pepper extract (piperine) helps enhance the absorption of other nutrients.

Also known as: piperine, Piper nigrum extract, Black pepper extract

Who should be careful

Our safety rules leave black pepper out of a formula, or keep the amount lower, with:

Medicines and supplements

• Estrogen pill
• Estrogen patch, gel, spray or pellets
• Estrogen / HRT
• Vaginal estrogen or DHEA
• Progesterone or a progestin
• Testosterone therapy
• Gender-affirming hormones: feminizing
• Gender-affirming hormones: masculinizing
• Gender-affirming hormone therapy
• Spironolactone
• Other anti-androgen
• GnRH medicine
• Birth control pill, patch or ring
• Progestin-only birth control
• Levothyroxine
• and 116 more

Procedures

• Organ or stem-cell transplant

Life stage

• Pregnancy
• Breastfeeding
• Trying to conceive

Always check with your doctor or pharmacist before adding a supplement if you take medication, are pregnant or nursing, or have a health condition.

Questions

How much black pepper a day?

apiece formulas usually include 5 mg a day.

What is black pepper used for?

Black pepper extract (piperine) helps enhance the absorption of other nutrients.*

Who should be careful with black pepper?

apiece’s safety rules leave it out or limit it with: Estrogen pill; Estrogen patch, gel, spray or pellets; Estrogen / HRT; Vaginal estrogen or DHEA; Progesterone or a progestin; Testosterone therapy; Gender-affirming hormones: feminizing; Gender-affirming hormones: masculinizing; Gender-affirming hormone therapy; Spironolactone and others. Check with your doctor or pharmacist if any apply to you.

Can I get black pepper in a personalized supplement?

Yes. apiece builds one daily blend around your goals and, if you have them, your lab results. Black pepper can be part of it at the amount listed, with every ingredient shown and never more than 10 capsules a day.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This page is general information, not medical advice. Check with your doctor or pharmacist before starting a supplement, especially if you take medication, are pregnant or nursing, or have a health condition. Updated 2026-10-21.